A study about Etomidate usage in patients undergoing certain surgical procedures?.
Risk for death more than doubled for critically ill in retrospective study
The authors of this clinical study made a claim that Etomidate is linked worst post surgical outcomes and including risks of death? but other expert anesthesiologist argued that the study is not conclusive (not a definitive study?), well a combination of anesthetics when used caution must be exercised, this is for anesthesiologists to keep in mind when they make their decision to use what anesthesia combination or regiment can make a safe outcome.
Etomidate Linked to Worse Post-op Outcomes vs. Propofol
Risk for death more than doubled for critically ill in retrospective study
by Michael Vlessides
Washington—Anesthesiologists tempted to use etomidate instead of propofol to induce anesthesia in critically ill patients might think twice after considering the results of a retrospective analysis by researchers at Cleveland Clinic. The analysis concluded that noncardiac patients given etomidate were two to three times more likely than those given propofol to die within 30 days.
“Although etomidate is sometimes used for general anesthesia induction in critically ill patients, the drug is known to cause prolonged adrenal impairment by blocking cortisol release,” said Ryu Komatsu, MD, a resident at the Ohio institution. “As we might suspect, worse outcomes have been reported in association with etomidate use in critically ill patients. However, the potential link between etomidate and worsened postoperative outcomes has not been systematically studied in general surgical patients.”
“Although etomidate is sometimes used for general anesthesia induction in critically ill patients, the drug is known to cause prolonged adrenal impairment by blocking cortisol release,” said Ryu Komatsu, MD, a resident at the Ohio institution. “As we might suspect, worse outcomes have been reported in association with etomidate use in critically ill patients. However, the potential link between etomidate and worsened postoperative outcomes has not been systematically studied in general surgical patients.”
Etomidate (USAN, INN, BAN) (marketed as Amidate) is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, and cardioversion. Etomidate
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