One of the most extensive research work of mine explores the ability of central nervous pathway "olfactory tract" regeneration following experimentally induced transection (simulation of certain type of traumatic damage), the results have already been published in many reputed journals, a fascinating finding indicating though CNS has limited abilities to regenerate, central tracts like olfactory pathway has enormous regenerative potentials even at the synaptic reorganization levels (Exp Neurol. 1997 Mar;144(1):174-82. Regeneration of the olfactory tract following neonatal lesion in rats. Munirathinam S et al). This special issue mostly covers the advancement in perception of chemical senses by using PET and fMRI imaging studies, a good read to update Olfactory Sense?.
Our knowledge regarding the neural processing of the three chemical senses has been considerably lagging behind that of our other senses. It is only during the last 25 years that significant advances have been made in our understanding of where in the human brain odors, tastants, and trigeminal stimuli are processed. Here, we provide an overview of the current knowledge of how the human brain processes chemical stimuli based on findings in neuroimaging studies using positron emission tomography and functional magnetic resonance imaging. Additionally, we provide new insights from recent meta-analyses, on the basis of all published neuroimaging studies of the chemical senses, of where the chemical senses converge in the brain.
http://pubs.acs.org/toc/acncdm/2/1
http://pubs.acs.org/toc/acncdm/2/1
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